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ONE conference 2022: MICROBIOMES, CHEMICALS AND HEALTH: UNRAVELLING AN INTRICATE TRIAD

June 23

The communities of microorganisms in a defined environment are collectively referred to as microbiomes, and they include Bacteria, Archaea, Eukarya and viruses. Microbiome structures and dynamics across the food system can have both direct and indirect effects on human, animal and soil health, thus occupying a central position in the One Health framework. The gut microbiome is currently viewed as an additional mediator of both potentially beneficial and adverse effects of dietary or environmental exposure to chemicals. Regarding soil microbiome, recent research directly attributes improved plant health and soil fertility to an optimal balance within soil microorganisms. It also appears that this balance may be impaired by several anthropogenic factors, such as plant protection products. Among the challenges to be addressed before integrating microbiome considerations into regulatory safety assessments are the following: (1) a lack of internationally agreed guidance to systematically account for possible effects on microbiomes or effects by microbiomes on host health; (2) the need for more knowledge on how the human microbiome modulates the pharmacokinetics and metabolism of chemicals; and (3) the hindering of translating a decrease in microbiome diversity into a functional consequence due to the absence of standards to define a healthy microbiome. This session aims to improve our understanding of the relevance of microbiome structural changes to chemical risk assessments. The main quest in this scientific domain is to enhance the evidence base that demonstrates the causality between a structurally altered microbiome and subsequent change(s) in metabolic pathways leading to adverse effects in the host.

Details

Date:
June 23
https://www.one2022.eu/

Other

Target Audience:
Microbiome Professionals, Adults, Students
Public or Private Event:
Anyone Can Join
Type of Event:
Hybrid Event

Venue

SQUARE
Mont des Arts
Brussels, 1000 Belgium
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